cartrophen (Nature Vet)與肘關節炎

[大敦寵物醫院]

shine426 : 戴醫師您好：

由於在網路搜尋Nature Vet時，看到在貴中心的討論區張貼回收Nature Vet產品的消息，所以來詢問有關該公司的另一項產品—即俗稱的“cartrophen”，藥品名是“Pentosan 100 Injection” (Pentosan Polysulfate Sodium, 100mg)。由於我六歲的German Shepard混種的狗狗(35公斤)有肘關節炎，澳洲的獸醫推薦試用這項產品，效果頗佳。它不是止痛藥或一般的消炎藥，主要的功能是促進血液循環與軟骨增生。我們的狗狗每月注射後，就大有改善，唯一個月將近時，就會再出現走路緩慢等症狀。
我想請問的是，臺灣有沒有可能找到這種藥品，如果沒有，有沒有比GLUCOSAMINE更有效的藥。下面所貼的文章，因為網址已變，只好全文張貼。由於圖片無法顯示，敬請見諒。

祝 秋祺

Shine 敬上

大敦寵物醫療中心院長戴更基醫生 : 因為您貼得太長,我先刪除了以利閱讀
cartrophen在美國之外是行以多年,但是在美國這方面是最近才開始使用的,目前評估的效果是不錯的,但是美國的做事方式總要等到幾年後的臨床評估結果出爐後才會廣泛的使用,我的用藥以美國方面為主,所以目前尚未使用此藥,據了解目前台灣也尚未進口!
雖然臨床的反應不錯,但是您並沒有看到問題的CASE,以下是英國的問題CASE,轉貼給您參考

I am sorry to hear about your problems regarding the use of Cartrophen Vet and the subsequent vestibular attack that your dog has suffered. In this case it is most likely to be the Cartrophen that was to blame for the vestibular attack but not for the brain tumours. As a clinician I use a lot of Cartrophen as it gives good results in 70 per cent or more cases and is economical to use but it does have one major complication. The action of Cartrophen is to stimulate the glandular tissue in the joint however this is not specific and you do get some stimulation of other glandular tissues which if cancerous can lead to more rapid growth of any undiagnosed mass.The main problem that occurs however is that the Cartrophen stops platelet aggregation or in other words stops blood clotting normally. This can lead to bleeding especially inside a mass. In this case the bleeding would have given rise to sudden increase in pressure in the brain causing your symptoms. Vivitonin acts to increase the oxygen availability in the brain without increasing blood pressure so will have helped to some degree initially but should not be used longer term in case it improves oxygenation of the brain tumours and increases their rate of growth. There has been work done more recently with diets at trying to improve tumour control. Hills make two diets which could be beneficial one is N/d which is specifically made for cancer patients and the other is B/d which is made for dogs with brain problems and may be beneficial. Neither diet will have any side effects apart from possible transient diarrhoea when you start. There is also a tablet called Activait that has been launched last week and should be in the wholesalers within the next 2 weeks that could be beneficial in slowing the brain tumours down. I hope you manage to get a fair period of reasonable quality life for a while to come.As for your other dog, it is always hard to try a treatment again when something has gone so badly wrong. Side-affects with Cartrophen are around one per cent which is quite high but the vast majority of these are not serious problems. There are also other treatments available especially non steroidals with Metacam and Rimadyl being probably the best and also the use of nutritional supplements like Synoquin or Cosequin that work very well in helping the cartilage to repair but can be expensive to use. Cheaper treatments include use of greenlip mussel or artphyton but in my personal experience these do not work in anywhere as many cases.I hope this has been of some benefit and if you need any further help just ask.Paul J. Wilson

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